Luminescent Ruthenium(II) Complex Bearing Bipyridine and N-Heterocyclic Carbene-based C∧N∧C Pincer Ligand for Live-Cell Imaging of Endocytosis

نویسندگان

  • Wai-Kuen Tsui
  • Lai-Hon Chung
  • Matthew Man-Kin Wong
  • Wai-Him Tsang
  • Hoi-Shing Lo
  • Yaxiang Liu
  • Chung-Hang Leung
  • Dik-Lung Ma
  • Sung-Kay Chiu
  • Chun-Yuen Wong
چکیده

Luminescent ruthenium(II)-cyanide complex with N-heterocyclic carbene pincer ligand C(∧)N(∧)C = 2,6-bis(1-butylimidazol-2-ylidene)pyridine and 2,2'-bipyridine (bpy) shows minimal cytotoxicity to both human breast carcinoma cell (MCF-7) and human retinal pigmented epithelium cell (RPE) in a wide range of concentration (0.1-500 μM), and can be used for the luminescent imaging of endocytosis of the complex in these cells.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2015